Interfacing Continuum and Discrete Methods: Convective Diffusion of Microparticles and Chemical Species in Microsystems

J. Berthier
CEA-LETI, Department of Biotechnology, Grenoble, France
Published in 2008

Convective transport of macromolecules or micro and nanoparticles in microsystems are usually predicted by solving the Navier Stokes equations for the carrier fluid and a concentration equation for the diffusing species. In the case of isolated particles or complicated geometries with extremely small apertures or microporous material, the concentration equation maybe replaced by a Monte Carlo model.

We have shown that interfacing Monte-Carlo diffusion with a PDE solution for the velocity field brings a new light to convective diffusion of solitary particles in the complex geometries of microsystems for biotechnology.

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