Harvey Buck, Roche Diagnostics Operations, Inc., Indianapolis, IN, USA
The test strips in glucose monitors, widely used by people with diabetes to maintain good health, are sensitive to chemical interferences and environmental conditions. The manufacturing process and electrode configuration of these strips also affects response accuracy. Researchers at Roche Diagnostics Operations, Inc. used multiphysics simulation to analyze the chemical reactions and voltage response in their glucometers.
Using COMSOL Multiphysics, Harvey Buck, principal scientist at Roche, investigated different configurations and materials used in the test strips. He analyzed the electrical response to an applied voltage during the chemical reaction catalyzed in a sample. Through numerical simulation, he predicted the sensitivity of electrical impedance measurements to mechanical properties of the sensor. He also optimized the electrode configuration, maximized sensitivity to cell fraction in a sample, and minimized sensitivity to manufacturing tolerances. These simulation results have given the Roche team a better understanding of their integrated sensor design for glucose monitoring.
Suggested Stories
Keynote: Optimum Electromagnetic and Thermal Design of DC-Link Capacitors
Inverters change the DC produced by an electric vehicle's battery into the AC needed to drive its motors. Inside these ...
Designing a Silicon Photonic MEMS Phase Shifter with Simulation
Researchers at the Swiss Federal Institute of Technology Lausanne are using simulation to optimize the optical and ...
National Grid Models Underground Cable Routes
U.K. National Grid bears responsibility for maintaining the high-voltage transmission network in the U.K. Determining ...
Refining Automotive Battery Management Systems with Lumped-Approach Thermal Modeling
India’s transportation sector is pursuing ambitious electrification goals, and so manufacturers must optimize battery ...
