Keynote: Simulating Lipid Nanoparticle Self-Assembly for mRNA Vaccine Production

Lipid nanoparticle (LNP) self-assembly is used for a variety of pharmaceutical applications, including mRNA vaccine production. In a keynote talk at COMSOL Day: Pharmaceutical Applications, Joseph Barakat and Matthew J. Hancock of Veryst Engineering, LLC, showed how simulating LNP self-assembly can greatly expedite the development of processes and devices, whether it be for production-scale applications or small-batch applications. They also shared how to use the COMSOL Multiphysics^® software to model LNP self-assembly and discussed how these models can be used to guide process and design decisions.

Joseph Barakat is a senior engineer at Veryst Engineering, LLC with core expertise in microfluidics, electrokinetics, surfactant and surface-tension effects, heat and mass transfer, and suspension mechanics. Matthew Hancock is a partner at Veryst Engineering, LLC, and consults on product design and performance projects related to fluid mechanics, specifically for areas such as microfluidics, surface tension and wetting, heat transfer, species transport, and mixing.