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Modeling Temperature Stability for Vaccine Transportation Using Dry Ice
Posted Mar 25, 2026, 9:41 a.m. EDT Chemical, Studies & Solvers, Modeling Workflow 1 Reply
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Hello everyone,
I am interested in modeling temperature distribution for vaccine transportation using dry ice in insulated containers. Since vaccines require strict cold chain conditions, maintaining a consistent low temperature during transit is critical.
I would like to understand how we can simulate:
Heat transfer inside an insulated box Sublimation effect of dry ice (CO₂ phase change) External temperature impact during transportation
Is it possible in COMSOL Multiphysics to couple heat transfer with phase change for dry ice cooling? If yes, which physics interface or module would be most suitable for this type of simulation?
Additionally, if anyone has experience with real-world cold chain applications (such as pharmaceutical logistics), I would appreciate insights on practical parameters to consider.
From a practical perspective, reliable dry ice supply and proper insulation are commonly used in the industry to maintain temperature stability during transport.
Looking forward to your suggestions and guidance.
Thank you.
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Hi Mehwish:
Linked is an article that shows how to use COMSOL Phase change material for your problem.
https://pubmed.ncbi.nlm.nih.gov/39832233/
